fat synthesis मीनिंग इन हिंदी

The first significant study was subsequently published by Fell and Small, who used flux balance analysis together with more elaborate objective functions to study the constraints in fat synthesis.
When ATP is depleted, there is a rise in 5'AMP . This rise activates AMP-activated protein kinase, which phosphorylates ACC and thereby inhibits fat synthesis.
The overall effect of these final enzyme dephosphorylations is that, in the tissues that can carry out these reactions, glycogen and fat synthesis from glucose are stimulated, and glucose production by the liver through glycogenolysis and gluconeogenesis are inhibited.
The phosphatase removes the phosphate from pyruvate dehydrogenase activating it and allowing for conversion of pyruvate to acetyl-CoA . This mechanism leads to the increased rate of catalysis of this enzyme, so increases the levels of acetyl-CoA . Increased levels of acetyl-CoA will increase the flux through not only the fat synthesis pathway but also the citric acid cycle.